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Start date: 2020Subject: search.filters.subject.Nigeria

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    Geoelectrical Characterization of Coastal Aquifers in Agbado-Ijaye, Lagos, Southwestern Nigeria; Implications for Groundwater Resources Sustainability
    (MDPI, Basel, Switzerland, 2023) Oyeyemi, Kehinde D.; Abuka-Joshua, Joyce; Rotimi, Oluwatosin J.; Dieppois, Bastien; Gomo, Modreck; Olaojo, Abayomi A.; Falae, Philips O.; Metwaly, Mohamed
    Water is a natural resource; its availability depends on climatic and geological conditions, and it is invariably controlled by human activities. Agbado-Ijaye lies within a coastal area, where local communities have been facing incessant water shortages, especially during the dry season. This study investigated the groundwater-bearing geological unit(s) using hydrogeophysical techniques in the coastal environment. The electrical resistivity technique, involving vertical electrical sounding (VES) and two-dimensional (2D) electrical resistivity imaging via Wenner array electrode configuration, was used to characterize the geoelectric distribution. Twenty VES stations were investigated and current electrodes (AB/2 m) spacing expanded from 1–200 m; four 2D electrical resistivity imaging traverses having a length of 200 m each and interelectrode spacing of 10 m (level 1) to 60 m (level 6) was adopted. Four geoelectric units were delineated, namely: topsoil (15–251 Ωm), clayey (28–100 Ωm), clayey sand (125–190 Ωm) and sandy (205–876 Ωm) with thicknesses ranging from 0.7–1.3 m, 4.1–19.0 m, 2.6–15.6 m and undefined depth, respectively. The 2D imaging sections also detected similar geoelectric layers, corroborating the VES-derived sections. The inverted sections delineated two different aquifers: the shallower low-yield aquifer comprising sandy clay/clayey sand units with a maximum depth of about 5.5 m. This layer is adjudged to be the continental plain sand of the Benin Formation. The deeper high-yield aquifer with a maximum depth of 30.4 m is a beach sand unit that belongs to the Tertiary Alluvium of the Dahomey Basin. The study showed that hydrogeophysical investigation is vital in exploring, developing, and managing coastal groundwater resources.
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    Government’s motives and investor’s commitment in public-private partnership procurement system adoption
    (Sciendo, 2025) Amusan, Lekan; Ojelabi, Rapheal Abiodun; Adewolu, Adeoye Olugbenga; Olanipekun, Oladeji Olubunmi
    The study examined the government’s motives - ment to infrastructure delivery. The study adopted a quan titative research method with a survey conducted using a structured questionnaire targeted at 384 respondents selected through random sampling. The data were ana lysed using mean, percentile and Pearson correlation sta tistical tools. The study identified 17 key motives respon sible for the government adopting PPP in socio-economic infrastructure delivery. These motives were factored into three main groups: public infrastructure maintenance, financial and economic benefits; improved discipline in the contractual relationship and predictable path in infra structure delivery and integration of innovative approach in enhancing infrastructure delivery. Therefore, the relationships between the three factored government’s motives and investor’s commitments, including finance, management, technical and operational services in PPP, were tested using the Pearson correlation statistical tool. The results showed that the motive for public infrastructure maintenance, financial and economic benefits of the government in PPP showed a significant relationship with the four services commitment of private partners. Also, the government’s motive for improved discipline in the contractual relationship and predictable path in infrastructure delivery showed significant relationships with technical, finance and management commit ments of investors. Lastly, the government’s motive for the integration of innovative approaches in enhancing infrastructure delivery showed a significant relationship with only technical commitment. The outcome indicates that factors measuring government motive and investor's services commitment are mutually dependent and critical in ensuring a sustained relationship among stakeholders in a PPP arrangement for infrastructure procurement.
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    Practitioners’ experiences with the drivers and practices for implementing sustainable construction in Nigeria: a qualitative assessment
    (Emerald Publishing Limited, 2020) Tunji-Olayeni, Patience; Kajimo-Shakantu, Kahilu; Osunrayi, Ewaoluwa
    Purpose – The purpose of this study is to assess the drivers, practices and policies for implementing sustainable construction in Nigeria. This is with a view towards increasing the rate of implementation and diffusion of sustainable construction practice, so that more Nigerians can benefit from its environmental, social and economic dividends. Design/methodology/approach – This study adopted a qualitative research design with the use of face-to face oral interviews. Interviewees were selected using a purposive sampling technique. Data from the interview were analysed using thematic analysis. Descriptive statistics of frequencies, percentages and rankings were also used to present the data and complement the thematic analysis. Findings – The study identified five major drivers of sustainable construction: clients’ demand, international pressure, corporate social responsibility, competitiveness and cost-effectiveness. The common sustainable practices adopted by the interviewees are compliance with health and safety regulation, waste management, energy efficiency and material reuse. The most appropriate policies for implementing sustainable construction as suggested by the interviewees were government regulations, provision of tax relief and subsidies and public awareness. A combination of regulatory policies, market-based policies and voluntary participation of stakeholders will enhance the attainment of sustainability transformations in the construction industry Originality/value – The study is based on the findings of construction participants who have practical experience with sustainable construction in Nigeria. The study also provides empirical evidences which could guide the design and implementation of policies that will further promote the diffusion of sustainable construction in Nigeria.
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    Stakeholders’ perspectives on addressing climate change and respiratory health impacts in Nigeria
    (Pan African Medical Journal, 2025) Akinnola, Olayemi O.; Iseolorunkanmi, Alexander; Niyi-Odumosu, Faatihah; Akinnola, Olayemi O.; Ale, Boni Maxime; Adeloye, Davies; Ozoh, Obianuju Beatrice
    The impacts of climate change on respiratory health are increasingly becoming a significant challenge in Nigerian cities, particularly in Lagos and Ogun States. Engaging stakeholders in discussions about climate change and health is crucial for addressing these challenges. The climate change and respiratory health (C2Rest) Nigeria Study team facilitated a stakeholder engagement to discuss climate change and health impacts in Nigeria, aiming to explore feasible solutions relevant to research, policy, and practice. A stakeholder meeting was conducted on April 23rd, 2024, involving from Gardner´s climate change engagement pathways, which examine key drivers (8 questions), barriers (7 questions), and adaptation pathways (3 questions). Data were collected through note-taking, written contributions, audio and video recording, and subsequently transcribed and analysed thematically. A total of 42 registered participants, comprising government officials, academicians, healthcare professionals, community and religious leaders, attended the stakeholder engagement meeting. Participants made group presentations and submitted a total of 380 written contributions. There were varying views on the drivers of climate change, but there was consensus that the most vulnerable populations include the poor, homeless, pregnant women, children, the elderly, and individuals with underlying health conditions. An important barrier identified was the sociocultural belief that climate change is an act of God or spirits. Financial constraints were a recurrent theme in discussions about mitigation and adaptation to climate change. This report provides valuable information on the most vulnerable population to the effects of climate change in Nigeria and identifies sociocultural beliefs and financial constraints as key barriers to the adoption of effective mitigation and adaptation behaviors.
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    KNOWLEDGE AND PRACTICES OF HEALTHCARE WORKERS ON ARBOVIRAL INFECTIONS AND DIAGNOSTICS APPROACH IN OGUN STATE, SOUTHWEST NIGERIA
    (Open Journal of Medical Research, 2024) Ipadeola, A. F.; Akinnola, Olayemi O.; Kolawole, O. M.; Isere, E. E.; Attah, T. A.; Omenyi, I. O.; Afekelu, O. D.; Oreoluwa, A. A.; Oludare, I. T.; Adediran, A. S.; Olasehinde, G. I.
    Arboviral infections pose significant public health challenges in tropical and subtropical regions like Nigeria. However, these diseases are often undetected by healthcare workers (HCWs) due to the similarity in the presentation to other febrile illnesses like malaria. This study assessed the knowledge and diagnostic practices of HCWs on arboviral infections in Ogun State. A cross-sectional study was conducted among HCWs in selected secondary and tertiary health facilities in Ogun State from October 2022 to September 2023. A semi-structured questionnaire was administered to collect data on sociodemographic characteristics, knowledge of arboviral infections, and diagnostic practices. Stata was used to analyze the data at a 5% level of significance. Of the 96 participants included in the study, 59.4% were female, and 40.0% were ≥35 years old. Nurses constituted the largest cadre (41.7%) while medical doctors (24.0%) were the least represented. Most respondents (68.8%) had never heard of arboviral infections, and 81.3% demonstrated poor knowledge about arboviral infections and diagnosis. Only 6.3% of HCWs had previously suspected or diagnosed an arboviral infection, with clinical diagnosis being more common (66.7%) than laboratory testing (33.3%). Notably, 92.7% of all respondents had no prior training in arboviral infection diagnosis. Good knowledge and previous training received were significantly associated with the diagnosis of arboviral infections among HCWs (p<.05). There is a gap in the knowledge and diagnostic practices of HCWs in the detection of arboviral infections in Ogun State. Thus, comprehensive training programs may be significant in improving awareness, and diagnostic capabilities and enhancing prompt detection and management of arboviral infections in Ogun state
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    Epidemiological and Seasonal Patterns of Respiratory Diseases at a Community Health Facility in Southwest Nigeria: A Five-Year Retrospective Analysis
    (The Open Public Health Journal, 2025) Oshamika, Oyewumi Oluwaseun; Adebanjo, Ademola Oyeyemi; Onile-ere, Olabode Azeez; Akinnola, Olayemi O.; Eni, Angela Obiagel
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    Prevalence and associated risk factors of Staphylococcus aureus nasal colonization among a cohort of immunocompromised individuals in Lagos, Nigeria
    (BMC Infectious Diseases, 2025) Ogunleye, Bimpe O.; Oshamika, Oyewumi O.; Akinpelu, Sharon O.; Ajayi, Ayodeji S.; Akinduti, Paul A.; Oyedeji, Kolawole S.; Odeniy, Olalekan M.; Akinnola, Olayemi O.
    Background Immunocompromised individuals are highly vulnerable to Staphylococcus aureus (S. aureus) infections, leading to increased morbidity and mortality. This study aimed to assess the prevalence, virulence, and risk factors associated with S. aureus nasal carriage among immunocompromised individuals in Lagos, Nigeria. Methods A total of 350 participants were enrolled, including 150 HIV/AIDS cases, 50 HIV/TB co-infections, 100 diabetes cases, and 50 controls. Nasal swabs were collected and cultured on Mannitol salt agar for the isolation of Staphylococcus aureus. Presumptive isolates were confirmed using Gram staining, catalase, and coagulase tests. Antimicrobial susceptibility was determined using the Kirby-Bauer disk diffusion method in accordance with CLSI guidelines. Molecular detection of resistance and virulence genes was performed using PCR targeting the mecA gene (methicillin resistance) and pvl (Panton-Valentine leukocidin). A structured questionnaire capturing clinical history and hygiene practices was used to evaluate risk factors for S. aureus carriage. Results The overall prevalence of S. aureus was 14.6% (51/350), S. aureus was isolated in 28% (14/50) of controls, 16.7% (25/150) of HIV/AIDS patients, 14% (7/50) of HIV/TB cases and 5% (5/100) of diabetes cases. Susceptibility to erythromycin was 80.4%, gentamycin, ciprofloxacin and Sulfamethoxazole-Trimethoprim (64.7%) among all S. aureus isolated. Methicillin-resistant S. aureus (MRSA) was detected in 78.4% (40/51) of isolates, predominantly among HIV/AIDS patients (52.5%). pvl genes were identified in 11.8% (6/51) of isolates. S. aureus carriage was significantly associated with recent antibiotic use (p = 0.003) and contact with animals (p = 0.018). Conclusion This study demonstrates a high prevalence of S. aureus among controls compared to immunocompromised individuals. These results highlight the need for further studies to elucidate the relationship between host factors and S. aureus colonization. This could inform targeted strategies for infection prevention and control.
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    Age-specific patterns of breast cancer in Nigerian women unraveled through histological analysis
    (Scientific Reports, 2025) Effiong, Magdalene Eno; Chinedu, Shalom Nwodo; Afolabi, Israel Sunmola; Ezike, Kevin Nwabueze; Oguntebi, Emmanuel Eyitayo; Abdul, Oluwasesan Adelowo; Achusi, Izuchukwu Benerdin; Benye, Tolulope Aanuoluwapo; Omunagbe, Mercy Bella; Ogbodo, Peace Nzubechukwu
    Sub-Saharan African women face a high burden of breast cancer, influenced by genetic and lifestyle factors. However, the lack of comprehensive, age-stratified data hinders the identification of risk factors and the development of effective, population-specific interventions. This study aimed to assess age-related variations in breast cancer prevalence among Nigerian women, providing insight into associated risk factors and disease trends. A retrospective review of 3,263 breast histopathology records (9.46% of total from 2015 to 2023) was conducted. Lesions—benign and malignant—were analyzed across five age groups: children and adolescents (0–19), young adults (20–39), middle-aged (40–59), higher-aged (60–79), and elderly (≥ 80), using MS Excel and GraphPad Prism 8.0. Statistical comparisons were performed by age and lesion type. Most cases were in young adults (45.97%) and middle-aged women (33.83%). The left breast was more commonly affected (46.86%) and had higher malignancy rates than the right (44.41%) or bilateral lesions (7.20%). Benign lesions were predominant (56.76%), especially among young adults (57.34%). Malignancy incidence increased with age, peaking in middle-aged women (53.30%). Fibroadenoma was the most frequent benign lesion in children and adolescents and young adults, while fibrosis predominated in middle age. Invasive ductal carcinoma (IDC) was the leading malignant subtype, with a sharp rise by 2023—particularly among middle-aged (172 cases) and young adult women (71 cases). Among 339 immunohistochemically profiled cases, triple-negative breast cancer (TNBC; 42.77%) and ER+/PR+ tumors (36.87%) were most common. TNBC was the only subtype detected in children and adolescents. Middle-aged women bore the highest burden of all subtypes, with a marked increase in TNBC and ER+/PR+ cases in 2023. The rising incidence of aggressive subtypes, particularly TNBC, highlights the need for enhanced molecular diagnostics and personalized therapies. Age-specific trends reinforce the urgency for targeted screening, especially for young and middle-aged Nigerian women.
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    Knowledge, practices, and perceptions towards malaria prevention and control among Residents of Canaanland and surrounding areas in Ota, Ogun State, Nigeria: a cross-sectional study
    (Frontiers in Tropical Diseases, 2025-10-13) Wakai, Theophilus N.; Fiamitia, Carrin; Kintung, Irrinus; Johngwe, Mac; Chinedu, Shalom; Afolabi, Israel S.
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    Exome sequencing in Nigerian children with early-onset epilepsy syndromes
    (Epilepsia Open, 2024-10-31) Ademuwagun, Ibitayo Abigail; Adam, Yagoub; Rotimi, Solomon Oladapo; Syrbe, Steffen; Radtke, Maximilian; Hentschel, Julia; Lemke, Johannes R.; Adebiyi, Ezekiel
    Objective: Nigeria, along with other Sub-Saharan African countries, bears the highest burden of epilepsy worldwide. This high prevalence is attributed to a combination of factors, including a significant incidence of infectious diseases, perinatal complications, and genetic etiologies. Genetic testing is rarely available and is not typically included in the routine diagnostic work-up for individuals with infantile and childhood epilepsy syndromes in these regions. Exome sequencing (ES) offers a diagnostic yield of 24%–62%, but these figures primarily reflect data from high-income countries (HICs) and may not be applicable to low-and middle-income countries (LMICs). In this study, we employed ES to investigate the genetic basis of early-onset epilepsy in 22 affected children from Nigeria. Methods: The study involved sampling of patients diagnosed with early-onset epilepsy syndromes at the Lagos State University Teaching Hospital (LASUTH) Neurology clinic. Venous blood samples were collected, and genomic DNA was isolated and purified. Molecular analysis included DNA fragmentation, ligation, target enrichment, library preparation, and whole-exome sequencing. Computational analysis involved variant calling, curation, and classification using specialized tools and databases. Results: Pathogenic variants were identified in 6 out of 22 individuals, equaling a diagnostic yield of 27.3% and comprising variants in BPTF, NAA15, SCN1A, TUBA1A and twice in CACNA1A. Significance: In this study, we present the first exome study on early-onset epilepsy syndromes from West Africa, facilitated by a Nigerian-German research collaboration. Our findings reveal a genetic diagnostic yield comparable to that of HICs. The integration of genomic medicine into epilepsy management in Nigeria holds promising prospects for improving patient care and reducing mortality rates