Advances in Plant Molecular Farming
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Description
Plant molecular farming (PMF) is a new branch of plant biotechnology, where plants are engineered to
produce recombinant pharmaceutical and industrial proteins in large quantities. As an emerging subdivision
of the biopharmaceutical industry, PMF is still trying to gain comparable social acceptance as the already
established production systems that produce these high valued proteins in microbial, yeast, or mammalian
expression systems. This article reviews the various cost-effective technologies and strategies, which are
being developed to improve yield and quality of the plant-derived pharmaceuticals, thereby making plantbased
production system suitable alternatives to the existing systems. It also attempts to overview the
different novel plant-derived pharmaceuticals and non-pharmaceutical protein products that are at various
stages of clinical development or commercialization. It then discusses the biosafety and regulatory issues,
which are crucial (if strictly adhered to) to eliminating potential health and environmental risks, which in
turn is necessary to earning favorable public perception, thus ensuring the success of the industry
Keywords
QH301 Biology, QR Microbiology, RM Therapeutics. Pharmacology