Effects of Solanum aethiopicum Fruit on Plasma Lipid Profile in rats
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Society of Education, India
Abstract
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To investigate the effects of the inclusion of graded levels of S. aethiopicum fruit in the feed of rats on plasma lipid profile.
20 male and 20 female rats were grouped into four groups of 5rats each per sex and fed on diets containing 0%, 4%, 8%
and 12% S. aethiopicum fruit for 28days. Thereafter, the plasma triacylglycerol, cholesterol, HDL cholesterol, VLDL
cholesterol and LDL cholesterol were estimated. Atherogenic and coronary indexes were also calculated. The diets
resulted in a significant (p < 0.05) reduction in plasma cholesterol, triacylglycerol, LDL cholesterol and VLDL cholesterol.
A significant (p < 0.05) increase in HDL cholesterol was also observed. The fruit also caused a significant (p < 0.05)
reduction in atherogenic and coronary risk indexed with female rats having better reduction. This work demonstrated
the ability of S. aethiopicum fruit to improved the lipid profile of the plasma thereby lowering the risk of cardiovascular
diseases
Keywords
QH301 Biology